Dlg3 - discs large MAGUK scaffold protein 3

Enables several functions, including PDZ domain binding activity; ionotropic glutamate receptor binding activity; and protein C-terminus binding activity. A structural constituent of postsynaptic density. Involved in positive regulation of protein tyrosine kinase activity. Located in several cellular components, including dendritic shaft; growth cone; and postsynaptic density. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 90. Orthologous to human DLG3 (discs large MAGUK scaffold protein 3). [provided by Alliance of Genome Resources, Apr 2022]