Dynll1 - dynein light chain LC8-type 1

Enables several functions, including identical protein binding activity; nitric-oxide synthase regulator activity; and scaffold protein binding activity. Involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus and spermatid development. Acts upstream of or within negative regulation of nitric oxide biosynthetic process. Located in axon cytoplasm; nucleus; and secretory granule. Part of cytoplasmic dynein complex. Colocalizes with mitochondrion. Used to study hypertension and impotence. Biomarker of cardiac arrest; congestive heart failure; and middle cerebral artery infarction. Orthologous to human DYNLL1 (dynein light chain LC8-type 1). [provided by Alliance of Genome Resources, Apr 2022]