Akr1a1 - aldo-keto reductase family 1, member A1 (aldehyde reductase)

Enables L-glucuronate reductase activity; alditol:NADP+ 1-oxidoreductase activity; and glucuronolactone reductase activity. Involved in cellular detoxification of aldehyde. Acts upstream of or within D-glucuronate catabolic process; L-ascorbic acid biosynthetic process; and aldehyde catabolic process. Located in apical plasma membrane and cytosol. Is active in synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human AKR1A1 (aldo-keto reductase family 1 member A1). [provided by Alliance of Genome Resources, Apr 2022]