Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Contributes to DNA binding activity. Involved in glucose mediated signaling pathway; positive regulation of fatty acid biosynthetic process; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; gut; liver; metanephros; and nose. Used to study irritable bowel syndrome. Orthologous to human MLXIPL (MLX interacting protein like). [provided by Alliance of Genome Resources, Apr 2022]