Sh3kbp1 - SH3-domain kinase binding protein 1

Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including actin filament organization; positive regulation of B cell activation; and regulation of cell shape. Predicted to act upstream of or within apoptotic process and endocytosis. Located in cell-cell junction and endocytic vesicle. Is expressed in embryo. Human ortholog(s) of this gene implicated in immunodeficiency 61. Orthologous to human SH3KBP1 (SH3 domain containing kinase binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]