Hacd3 - 3-hydroxyacyl-CoA dehydratase 3

Predicted to enable 3-hydroxyacyl-CoA dehydratase activity and enzyme binding activity. Acts upstream of or within I-kappaB kinase/NF-kappaB signaling; JNK cascade; and Rho protein signal transduction. Predicted to be located in endoplasmic reticulum and nuclear membrane. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including adrenal gland; central nervous system; gonad; retina; and spleen. Orthologous to human HACD3 (3-hydroxyacyl-CoA dehydratase 3). [provided by Alliance of Genome Resources, Apr 2022]