Jmy - junction-mediating and regulatory protein

Enables transcription coactivator activity. Involved in several processes, including actin nucleation; actin polymerization-dependent cell motility; and positive regulation of DNA-binding transcription factor activity. Acts upstream of or within intrinsic apoptotic signaling pathway by p53 class mediator and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in skeletal muscle. Orthologous to human JMY (junction mediating and regulatory protein, p53 cofactor). [provided by Alliance of Genome Resources, Apr 2022]