Isg20 - interferon-stimulated protein

Predicted to enable 3'-5' exonuclease activity and RNA binding activity. Predicted to be involved in defense response to virus; negative regulation of viral genome replication; and nucleobase-containing compound catabolic process. Predicted to act upstream of or within innate immune response and rRNA processing. Predicted to be located in cytoplasm and nuclear lumen. Predicted to be active in nucleus. Is expressed in liver lobe. Orthologous to human ISG20 (interferon stimulated exonuclease gene 20). [provided by Alliance of Genome Resources, Apr 2022]