Gmnn - geminin

Enables DNA-binding transcription factor binding activity and transcription corepressor activity. Involved in negative regulation of cell cycle; negative regulation of cellular macromolecule biosynthetic process; and protein-containing complex assembly. Acts upstream of or within animal organ morphogenesis. Located in nucleus. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and respiratory system. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 6. Orthologous to human GMNN (geminin DNA replication inhibitor). [provided by Alliance of Genome Resources, Apr 2022]