Jph3 - junctophilin 3

Involved in several processes, including exploration behavior; regulation of neuronal synaptic plasticity; and regulation of ryanodine-sensitive calcium-release channel activity. Acts upstream of or within learning; locomotion; and neuromuscular process controlling balance. Located in endoplasmic reticulum membrane and plasma membrane. Part of junctional membrane complex. Is expressed in brain. Human ortholog(s) of this gene implicated in Huntington's disease-like 2. Orthologous to human JPH3 (junctophilin 3). [provided by Alliance of Genome Resources, Apr 2022]