Slurp1 - secreted Ly6/Plaur domain containing 1

Predicted to enable acetylcholine receptor activator activity. Acts upstream of or within several processes, including negative regulation of cell migration; negative regulation of keratinocyte proliferation; and neuromuscular process controlling posture. Predicted to be located in extracellular space. Is expressed in cornea. Used to study mal de Meleda. Human ortholog(s) of this gene implicated in mal de Meleda and palmoplantar keratosis. Orthologous to human SLURP1 (secreted LY6/PLAUR domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]