Htr3b - 5-hydroxytryptamine (serotonin) receptor 3B

Enables serotonin-gated cation-selective channel activity. Predicted to be involved in several processes, including chemical synaptic transmission; positive regulation of ion transmembrane transporter activity; and regulation of membrane potential. Predicted to act upstream of or within ion transport. Is integral component of plasma membrane. Is expressed in several structures, including adrenal gland; genitourinary system; gut; lung; and nervous system. Human ortholog(s) of this gene implicated in alcohol use disorder and mental depression. Orthologous to human HTR3B (5-hydroxytryptamine receptor 3B). [provided by Alliance of Genome Resources, Apr 2022]