Stap1 - signal transducing adaptor family member 1

Enables macrophage colony-stimulating factor receptor binding activity and transmembrane receptor protein tyrosine kinase adaptor activity. Involved in several processes, including negative regulation of macrophage colony-stimulating factor signaling pathway; negative regulation of macrophage migration; and positive regulation of cellular component organization. Acts upstream of or within response to bacterium and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of protein-containing complex. Orthologous to human STAP1 (signal transducing adaptor family member 1). [provided by Alliance of Genome Resources, Apr 2022]