Notch3 - notch receptor 3

Predicted to enable enzyme binding activity; identical protein binding activity; and signaling receptor activity. Involved in several processes, including Notch signaling pathway; tissue regeneration; and wound healing. Predicted to be located in actin cytoskeleton; cytosol; and nucleoplasm. Predicted to be part of receptor complex. Predicted to be active in cell surface and plasma membrane. Human ortholog(s) of this gene implicated in CADASIL 1; infantile myofibromatosis; and lateral meningocele syndrome. Orthologous to human NOTCH3 (notch receptor 3). [provided by Alliance of Genome Resources, Apr 2022]