Ankrd2 - ankyrin repeat domain 2 (stretch responsive muscle)

Enables chromatin binding activity; protein kinase B binding activity; and titin binding activity. Involved in negative regulation of myoblast differentiation. Acts upstream of or within several processes, including negative regulation of myotube differentiation; regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and skeletal muscle cell differentiation. Located in several cellular components, including PML body; euchromatin; and sarcomere. Colocalizes with I band. Is expressed in skeletal musculature; somite; and tongue. Orthologous to human ANKRD2 (ankyrin repeat domain 2). [provided by Alliance of Genome Resources, Apr 2022]