Cilk1 - ciliogenesis associated kinase 1

Enables protein serine/threonine kinase activity. Involved in cilium organization and protein phosphorylation. Located in several cellular components, including ciliary basal body; ciliary base; and ciliary tip. Is expressed in several structures, including adipose tissue; alimentary system; eye; genitourinary system; and nervous system. Used to study endocrine-cerebro-osteodysplasia syndrome. Human ortholog(s) of this gene implicated in endocrine-cerebro-osteodysplasia syndrome and juvenile myoclonic epilepsy 10. Orthologous to human CILK1 (ciliogenesis associated kinase 1). [provided by Alliance of Genome Resources, Apr 2022]