Pex3 - peroxisomal biogenesis factor 3

Predicted to enable lipid binding activity and protein-macromolecule adaptor activity. Predicted to be involved in peroxisome membrane biogenesis and protein import into peroxisome membrane. Predicted to be located in several cellular components, including endoplasmic reticulum; nucleoplasm; and peroxisomal membrane. Predicted to be integral component of plasma membrane. Predicted to be part of protein-lipid complex. Predicted to be integral component of peroxisomal membrane. Is expressed in cerebral cortex ventricular layer and cortical plate. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and peroxisome biogenesis disorder 10A. Orthologous to human PEX3 (peroxisomal biogenesis factor 3). [provided by Alliance of Genome Resources, Apr 2022]