Mast1 - microtubule associated serine/threonine kinase 1

Enables microtubule binding activity. Involved in brain development and cytoskeleton organization. Located in membrane; neuron projection; and neuronal cell body. Is expressed in nervous system; neural retina; and skeletal muscle. Used to study mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations. Human ortholog(s) of this gene implicated in mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations. Orthologous to human MAST1 (microtubule associated serine/threonine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]