Enables CCR6 chemokine receptor binding activity. Involved in chemotaxis; defense response to Gram-negative bacterium; and defense response to Gram-positive bacterium. Acts upstream of or within defense response to bacterium. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human DEFB4B (defensin beta 4B). [provided by Alliance of Genome Resources, Apr 2022]