Slc22a21 - solute carrier family 22 (organic cation transporter), member 21

Enables carnitine transmembrane transporter activity. Acts upstream of or within carnitine transport. Located in peroxisome. Is intrinsic component of peroxisomal membrane. Is expressed in several structures, including genitourinary system; liver; lung; nasal cavity mucosa; and spleen. Human ortholog(s) of this gene implicated in Crohn's disease; cardiomyopathy; inherited metabolic disorder; and systemic primary carnitine deficiency disease. Orthologous to human SLC22A5 (solute carrier family 22 member 5). [provided by Alliance of Genome Resources, Apr 2022]