Pard6a - par-6 family cell polarity regulator alpha

Enables GTP-dependent protein binding activity and small GTPase binding activity. Involved in cell-cell junction maintenance and positive regulation of protein secretion. Acts upstream of or within negative regulation of protein phosphorylation. Located in several cellular components, including apical part of cell; bicellular tight junction; and cell cortex. Is expressed in several structures, including 2-cell stage conceptus; brain; gut; lung; and reproductive system. Orthologous to human PARD6A (par-6 family cell polarity regulator alpha). [provided by Alliance of Genome Resources, Apr 2022]