Snx1 - sorting nexin 1

Predicted to enable phosphatidylinositol binding activity; protein dimerization activity; and signaling receptor binding activity. Involved in neuron projection development. Acts upstream of or within negative regulation of transforming growth factor beta receptor signaling pathway. Located in several cellular components, including dendritic spine; early endosome; and postsynaptic density. Is active in postsynaptic density, intracellular component. Is extrinsic component of postsynaptic endosome membrane. Is expressed in embryo; epiblast; primitive endoderm; and yolk sac. Orthologous to human SNX1 (sorting nexin 1). [provided by Alliance of Genome Resources, Apr 2022]