Pdcd10 - programmed cell death 10

Predicted to enable protein N-terminus binding activity; protein homodimerization activity; and protein kinase binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in cytosol. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in Golgi apparatus. Is expressed in several structures, including cardiovascular system; central nervous system; gut; retina layer; and umbilical artery. Used to study cerebral cavernous malformation 3. Human ortholog(s) of this gene implicated in cerebral cavernous malformation 3. Orthologous to human PDCD10 (programmed cell death 10). [provided by Alliance of Genome Resources, Apr 2022]