Kcnj1 - potassium inwardly-rectifying channel, subfamily J, member 1

Predicted to enable several functions, including ATP-activated inward rectifier potassium channel activity; anion binding activity; and potassium ion binding activity. Acts upstream of or within several processes, including regulation of G-protein activated inward rectifier potassium channel activity; renal sodium ion absorption; and tissue homeostasis. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in heart and metanephros. Used to study Bartter disease type 2. Human ortholog(s) of this gene implicated in Bartter disease type 2. Orthologous to human KCNJ1 (potassium inwardly rectifying channel subfamily J member 1). [provided by Alliance of Genome Resources, Apr 2022]