Enables endopeptidase activity. Predicted to be involved in negative regulation of cellular protein metabolic process; negative regulation of protein localization to plasma membrane; and positive regulation of autophagy. Predicted to act upstream of or within autophagy. Predicted to be located in Golgi cis cisterna; Golgi medial cisterna; and Golgi trans cisterna. Predicted to be active in late endosome and lysosome. Is expressed in several structures, including alveolar sulcus; central nervous system; olfactory epithelium; retina; and skeleton. Orthologous to human TMEM59 (transmembrane protein 59). [provided by Alliance of Genome Resources, Apr 2022]