Fzr1 - fizzy and cell division cycle 20 related 1

Predicted to enable anaphase-promoting complex binding activity and ubiquitin ligase activator activity. Involved in negative regulation of cell aging and positive regulation of cell population proliferation. Acts upstream of or within lens fiber cell differentiation; proteolysis involved in cellular protein catabolic process; and regulation of meiotic nuclear division. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be part of anaphase-promoting complex. Is expressed in several structures, including central nervous system; liver; oocyte; sensory organ; and skeleton. Orthologous to human FZR1 (fizzy and cell division cycle 20 related 1). [provided by Alliance of Genome Resources, Apr 2022]