Ptges3 - prostaglandin E synthase 3

Enables DNA polymerase binding activity. Involved in positive regulation of telomerase activity; telomerase holoenzyme complex assembly; and telomere maintenance via telomerase. Acts upstream of or within several processes, including glucocorticoid receptor signaling pathway; glycogen biosynthetic process; and prostaglandin biosynthetic process. Predicted to be located in several cellular components, including actin filament; neuronal cell body; and perinuclear region of cytoplasm. Predicted to be part of chaperone complex and telomerase holoenzyme complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including liver and skin. Orthologous to human PTGES3 (prostaglandin E synthase 3). [provided by Alliance of Genome Resources, Apr 2022]