Ube2j1 - ubiquitin-conjugating enzyme E2J 1

Predicted to enable ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Acts upstream of or within regulation of tumor necrosis factor production; spermatid development; and ubiquitin-dependent ERAD pathway. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; nervous system; reproductive system; sensory organ; and skeleton. Orthologous to human UBE2J1 (ubiquitin conjugating enzyme E2 J1). [provided by Alliance of Genome Resources, Apr 2022]