Mad2l1 - MAD2 mitotic arrest deficient-like 1

Predicted to enable protein C-terminus binding activity and protein homodimerization activity. Involved in negative regulation of apoptotic process and positive regulation of mitotic cell cycle spindle assembly checkpoint. Acts upstream of or within mitotic sister chromatid segregation and mitotic spindle assembly checkpoint signaling. Located in several cellular components, including kinetochore; nucleus; and spindle pole. Is expressed in several structures, including central nervous system; genitourinary system; and retina. Orthologous to human MAD2L1 (mitotic arrest deficient 2 like 1). [provided by Alliance of Genome Resources, Apr 2022]