Cts8 - cathepsin 8

Predicted to enable several functions, including collagen binding activity; fibronectin binding activity; and serpin family protein binding activity. Acts upstream of or within blood vessel remodeling; protein catabolic process; and trophoblast giant cell differentiation. Located in extracellular region. Is expressed in several structures, including extraembryonic component; genitourinary system; heart; liver; and lung. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy. Orthologous to human CTSL (cathepsin L). [provided by Alliance of Genome Resources, Apr 2022]