Hgs - hepatocyte growth factor-regulated tyrosine kinase substrate

Predicted to enable several functions, including identical protein binding activity; ubiquitin-dependent protein binding activity; and ubiquitin-like protein ligase binding activity. Involved in endosome to lysosome transport. Located in cytosol; membrane; and secretory granule. Orthologous to human HGS (hepatocyte growth factor-regulated tyrosine kinase substrate). [provided by Alliance of Genome Resources, Apr 2022]