Tgm2 - transglutaminase 2

Enables GTP binding activity; identical protein binding activity; and protein domain specific binding activity. Involved in several processes, including isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; positive regulation of I-kappaB kinase/NF-kappaB signaling; and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway. Located in several cellular components, including cytosol; mitochondrion; and nucleus. Orthologous to human TGM2 (transglutaminase 2). [provided by Alliance of Genome Resources, Apr 2022]