Mpc1 - mitochondrial pyruvate carrier 1

Contributes to pyruvate transmembrane transporter activity. Acts upstream of or within cellular response to leukemia inhibitory factor; mitochondrial acetyl-CoA biosynthetic process from pyruvate; and mitochondrial pyruvate transmembrane transport. Located in mitochondrial inner membrane. Is expressed in several structures, including adrenal gland; hemolymphoid system; nervous system; olfactory epithelium; and retina. Human ortholog(s) of this gene implicated in mitochondrial pyruvate carrier deficiency. Orthologous to human MPC1 (mitochondrial pyruvate carrier 1). [provided by Alliance of Genome Resources, Apr 2022]