Tyk2 - tyrosine kinase 2

Predicted to enable growth hormone receptor binding activity; protein tyrosine kinase activity; and type 1 angiotensin receptor binding activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. Predicted to act upstream of or within phosphorylation. Predicted to be located in cytoplasm and nucleus. Used to study obesity. Human ortholog(s) of this gene implicated in immunodeficiency 35. Orthologous to human TYK2 (tyrosine kinase 2). [provided by Alliance of Genome Resources, Apr 2022]