Usp27x - ubiquitin specific peptidase 27, X chromosome

Enables Lys48-specific deubiquitinase activity; Lys63-specific deubiquitinase activity; and thiol-dependent deubiquitinase. Involved in positive regulation of apoptotic process; protein deubiquitination; and protein stabilization. Predicted to be located in cytoplasm and nucleus. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 105. Orthologous to human USP27X (ubiquitin specific peptidase 27 X-linked). [provided by Alliance of Genome Resources, Apr 2022]