Prickle3 - prickle planar cell polarity protein 3

Predicted to enable zinc ion binding activity. Predicted to act upstream of or within cell projection organization. Located in mitochondrion. Is expressed in several structures, including ear; early conceptus; female reproductive system; lower urinary tract; and nervous system. Used to study Leber plus disease. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy. Orthologous to human PRICKLE3 (prickle planar cell polarity protein 3). [provided by Alliance of Genome Resources, Apr 2022]