Sfrp5 - secreted frizzled-related sequence protein 5

Predicted to enable Wnt-protein binding activity. Acts upstream of or within several processes, including negative regulation of JUN kinase activity; post-anal tail morphogenesis; and regulation of establishment of planar polarity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; ear; early conceptus; embryo endoderm; and nervous system. Orthologous to human SFRP5 (secreted frizzled related protein 5). [provided by Alliance of Genome Resources, Apr 2022]