Iqgap2 - IQ motif containing GTPase activating protein 2

Predicted to enable several functions, including Arp2/3 complex binding activity; GTPase activator activity; and calmodulin binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation; regulation of actin cytoskeleton reorganization; and thrombin-activated receptor signaling pathway. Located in microvillus. Is expressed in several structures, including alimentary system; axial skeleton; central nervous system; genitourinary system; and liver. Used to study hepatocellular carcinoma. Orthologous to human IQGAP2 (IQ motif containing GTPase activating protein 2). [provided by Alliance of Genome Resources, Apr 2022]