Slc4a4 - solute carrier family 4 (anion exchanger), member 4

Predicted to enable identical protein binding activity and sodium:bicarbonate symporter activity. Involved in regulation of intracellular pH. Acts upstream of or within bicarbonate transport and sodium ion transport. Predicted to be located in cell surface and membrane. Predicted to be active in basolateral plasma membrane. Is expressed in several structures, including brain; metanephros; spinal cord floor plate; and thyroid primordium. Used to study renal tubular acidosis. Human ortholog(s) of this gene implicated in renal tubular acidosis. Orthologous to human SLC4A4 (solute carrier family 4 member 4). [provided by Alliance of Genome Resources, Apr 2022]