Arc - activity-regulated cytoskeleton-associated protein
Alias:
rg3.1
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Sequence Homology
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Enables mRNA binding activity. Involved in several processes, including learning or memory; positive regulation of AMPA receptor activity; and regulation of synaptic plasticity. Located in actin cytoskeleton and extracellular vesicle. Is active in glutamatergic synapse; postsynaptic density membrane; and postsynaptic endosome. Biomarker of middle cerebral artery infarction and visual epilepsy. Orthologous to human ARC (activity regulated cytoskeleton associated protein). [provided by Alliance of Genome Resources, Apr 2022]