Ncor1 - nuclear receptor co-repressor 1

Enables several functions, including RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; nuclear receptor binding activity; and peroxisome proliferator activated receptor binding activity. Involved in animal organ development; negative regulation of macromolecule metabolic process; and positive regulation of cell population proliferation. Located in nucleus and perinuclear region of cytoplasm. Used to study anxiety disorder and polycystic ovary syndrome. Biomarker of hypothyroidism and polycystic ovary syndrome. Orthologous to human NCOR1 (nuclear receptor corepressor 1). [provided by Alliance of Genome Resources, Apr 2022]