Nr4a2 - nuclear receptor subfamily 4, group A, member 2

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; negative regulation of neuron apoptotic process; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within response to inorganic substance and response to insecticide. Located in chromatin; cytoplasm; and nucleus. Biomarker of Parkinsonism and epilepsy. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human NR4A2 (nuclear receptor subfamily 4 group A member 2). [provided by Alliance of Genome Resources, Apr 2022]