Cxcr1 - C-X-C motif chemokine receptor 1

Predicted to enable chemokine binding activity and chemokine receptor activity. Predicted to be involved in several processes, including neutrophil chemotaxis; positive regulation of cytosolic calcium ion concentration; and receptor internalization. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Biomarker of membranoproliferative glomerulonephritis. Human ortholog(s) of this gene implicated in human immunodeficiency virus infectious disease; pyelonephritis; and urinary tract infection. Orthologous to human CXCR1 (C-X-C motif chemokine receptor 1). [provided by Alliance of Genome Resources, Apr 2022]