Gata4 - GATA binding protein 4

Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; NFAT protein binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell growth involved in cardiac muscle cell development; positive regulation of BMP signaling pathway; and transdifferentiation. Located in nucleus. Used to study myocardial infarction. Biomarker of congenital heart disease and pulmonary hypertension. Human ortholog(s) of this gene implicated in congenital heart disease (multiple). Orthologous to human GATA4 (GATA binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]