Predicted to enable several functions, including Hsp90 protein binding activity; guanylate cyclase activity; and heme binding activity. Predicted to contribute to adenylate cyclase activity and cytidylate cyclase activity. Involved in cGMP-mediated signaling and trans-synaptic signaling by nitric oxide, modulating synaptic transmission. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Predicted to be active in presynaptic active zone. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Orthologous to human GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]