Celsr2 - cadherin, EGF LAG seven-pass G-type receptor 2

Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Involved in several processes, including Wnt signaling pathway; homophilic cell adhesion via plasma membrane adhesion molecules; and neural plate anterior/posterior regionalization. Acts upstream of or within several processes, including cerebrospinal fluid secretion; cilium movement; and nervous system development. Located in cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and visual system. Used to study hydrocephalus. Orthologous to human CELSR2 (cadherin EGF LAG seven-pass G-type receptor 2). [provided by Alliance of Genome Resources, Apr 2022]