Chst3 - carbohydrate sulfotransferase 3

Enables chondroitin 6-sulfotransferase activity and proteoglycan sulfotransferase activity. Acts upstream of or within T cell homeostasis and chondroitin sulfate biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in trans-Golgi network. Is expressed in several structures, including brain; genitourinary system; gut; immune system; and respiratory system. Used to study schizophrenia. Human ortholog(s) of this gene implicated in osteochondrodysplasia and spondyloepiphyseal dysplasia with congenital joint dislocations. Orthologous to human CHST3 (carbohydrate sulfotransferase 3). [provided by Alliance of Genome Resources, Apr 2022]