Sco1 - SCO1 cytochrome c oxidase assembly protein

Predicted to enable metal ion binding activity. Acts upstream of or within several processes, including cyclooxygenase pathway; mitochondrial cytochrome c oxidase assembly; and negative regulation of protein kinase B signaling. Located in mitochondrion. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; liver; submandibular gland primordium; and vascular element. Used to study cytochrome-c oxidase deficiency disease. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human SCO1 (synthesis of cytochrome C oxidase 1). [provided by Alliance of Genome Resources, Apr 2022]