E2f7 - E2F transcription factor 7

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including hepatocyte differentiation; regulation of cell cycle process; and trophoblast giant cell differentiation. Acts upstream of or within negative regulation of cell population proliferation and regulation of transcription, DNA-templated. Located in nucleus. Is expressed in brain; embryo mesenchyme; and genitourinary system. Orthologous to human E2F7 (E2F transcription factor 7). [provided by Alliance of Genome Resources, Apr 2022]