Preb - prolactin regulatory element binding

Enables GTPase binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including COPII vesicle coating; protein transport; and regulation of COPII vesicle coating. Predicted to act upstream of or within protein transport and vesicle-mediated transport. Predicted to be located in endoplasmic reticulum exit site and nucleus. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; jaw; metanephros; and surface ectoderm. Orthologous to human PREB (prolactin regulatory element binding). [provided by Alliance of Genome Resources, Apr 2022]